OUR infertility 101
This post chronicles what we've done up until now to have a baby. Please email (or call) if you have any further questions, or want more details. There are
always more details!
(please click on the links for more information about that particular term)After my first miscarriage in December 2005, I talked to my ob/gyn about perhaps starting
Clomid. I had thought that I might have
low progesterone, and Clomid is supposed to help that. Before starting Clomid, we did
bloodwork for 3 months/cycles to see if I did indeed have
low progesterone, and if I was
ovulating at all. My Dr. gave me the prescription to start Clomid, but they didn't do any monitoring. Fearing
high order mutiples, I started going to the
RE.
My RE wanted a bunch of tests done first.
Bloodwork and an
HSG to see if my tubes were open and if there were any uterine abnormalities. All clear. With the clomid, they did do the monitoring to see how many eggs I had, then I got a
trigger shot of HCGt to aid ovulation.
We did that for 3 cycles.
It didn't work.The next step was to try the clomid with an
IUI. We did that for one cycle.
It didn't work.Since Clomid is a peculiar drug, most doctors only recommend being on it 4-6 cycles, but since it hadn't produced great results, our RE recommended moving on to Injectibles.
We did one cycle of
injectibles.
150iu of Follistim with another
IUI, which got me/us 4 eggs.
It didn't work.Then we decided to do more
extensive testing on D. That's when we got the first really bad news. The
genetic testing came back fine. It was the
morphology that was the deal breaker. Only 2% normal, using the
WHO guidelines.
Motility and count were also bad, but not serious. The RE said it would be a waste of our time and money to continue w/ the IUIs or Clomid, and he suggested going directly to
IVF w/ ICSI.
Oh, and then I got pregnant... but that only lasted a week. Highest
beta was 580.
I started the meds for the IVF cycle in December for the February cycle. I did the
long lupron protocol that time. That got us awful results w/ only 4 mature eggs. Only 2 of those eggs even fertilized, so they put them back 48 hours after the retrieval.
It didn't work.Then we took some Time Off. I said I was only doing IVF one more time...
IVF #2 started in June. Let me just say that this was a very rollercoaster cycle! We did the
microdose lupron flare protocol this time. was on the meds for a particularly long time-- 16 days. Read this for more info on
poor ovarian response. So, onto the cycle details; The first ultrasound is supposed to show your
antral follicle count. That number is basically how many eggs you have to work with during that cycle. I had NONE. The second ultrasound is after 5 days of the meds. I only had TWO follicles growing. By the time u/s 3 came around, 5 days later, I fully expected the cycle to get
cancelled, because by all measures it should have been.
Magically I had 10 follicles then, and we kept on going. Better results, as far as quantity goes, but the
egg quality was similarly bad. The embryologist suggested doing
assisted hatching because of the
dark zonas on my eggs. That means the shells are hard and once an embryo starts to grow, it can get stuck in the shell b/c it can't 'hatch' out of the thick shell. Read this for more info on
poor ovarian response. But because of that, we had more to play with and 3 were decent. We transferred 3 embryos 72 hours after retrieval and were given a 1 in 6 chance of triplets.
It didn't work.So here we are... trying to figure out what to do next.
We have a consult with
one of the best clinics in the country next month--
Colorado Center for Reproductive Medicine.